Mycophenolate mofetil
| Name | Mycophenolate mofetil |
| CAS No. | 115007-34-6 |
| Sepcification | USP42 |
| Usage and indications | Mycophenolate is used for the prevention of organ transplant rejection. Mycophenolate mofetil is indicated for the prevention of organ transplant rejection in adults and kidney transplantation rejection in children over 2 years; whereas mycophenolate sodium is indicated for the prevention of kidney transplant rejection in adults. Mycophenolate sodium has also been used for the prevention of rejection in liver, heart, or lung transplants in children older than two years |
| Structural formaula |  |
| Description | 1. Dosage form and Mechanism of action Dosage form: Tablets/Capsules Mechanism of action: Purines (including the nucleotides guanosine and adenosine) can either be synthesized de novo using ribose 5-phosphate or they can be salvaged from free nucleotides. Mycophenolic acid is potent, reversible, non-competitive inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH), an enzyme essential to the de novo synthesis of guanosine-5'-monophosphate (GMP) from inosine-5'-monophosphate (IMP). IMPDH inhibition particularly affects lymphocytes since they rely almost exclusively on de novo purine synthesis. In contrast, many other cell types use both pathways, and some cells, such as terminally differentiated neurons, depend completely on purine nucleotide salvage. Thus, use of mycophenolic acid leads to a relatively selective inhibition of DNA replication in T cells and B cells. 2. Specification Regarding the detailed standard, please contact info@shjnj.com 3. Package 10 kgs /bag; It can also be packed according to the requirements 4. Product source Produced by Chemical synthesis in China 5. Document support SMF and DMF are available 6. Supply Annual capacity: 5000 MT; Stable supply for more than 5 years If you need, Please contact us：info@shjnj.com |
