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Name Daptomycin
CAS No. 103060-53-3
Sepcification Enterprise standard
Usage and indications Daptomycin is indicated for use in adults for skin and skin structure infections caused by Gram-positive infections, S. aureus bacteraemia, and right-sided S. aureus endocarditis. It binds avidly to pulmonary surfactant, so cannot be used in the treatment of pneumonia. There seems to be a difference in working daptomycin on hematogenous pneumonia.
Structural formaula

1. Dosage form and Mechanism of action

KR: 답토마이신

JPN: ダプトマイシン

Dosage form: Injection

Mechanism of action: Daptomycin has a distinct mechanism of action, disrupting multiple aspects of bacterial cell membrane function. It inserts into the cell membrane in a phosphatidylglycerol-dependent fashion, where it then aggregates. The aggregation of daptomycin alters the curvature of the membrane, which creates holes that leak ions. This causes rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death.

2. Specification

Regarding the detailed standard, please contact info@shjnj.com

3. Package

1 kg/bag; 5 kgs/bag;

It can also be packed according to the requirements

4. Product source

Produced by fermentation in China

5. Document support

SMF and DMF are available

6. Supply

    Annual capacity: 5 MT; Stable supply for more than 10 years

If you need, Please contact us:info@shjnj.com

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Post Code:201114 Tel:021-50911366 Fax:021-50911377