Daptomycin
Name | Daptomycin |
CAS No. | 103060-53-3 |
Sepcification | Enterprise standard |
Usage and indications | Daptomycin is indicated for use in adults for skin and skin structure infections caused by Gram-positive infections, S. aureus bacteraemia, and right-sided S. aureus endocarditis. It binds avidly to pulmonary surfactant, so cannot be used in the treatment of pneumonia. There seems to be a difference in working daptomycin on hematogenous pneumonia. |
Structural formaula | |
Description | 1. Dosage form and Mechanism of action KR: 답토마이신 JPN: ダプトマイシン Dosage form: Injection Mechanism of action: Daptomycin has a distinct mechanism of action, disrupting multiple aspects of bacterial cell membrane function. It inserts into the cell membrane in a phosphatidylglycerol-dependent fashion, where it then aggregates. The aggregation of daptomycin alters the curvature of the membrane, which creates holes that leak ions. This causes rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death. 2. Specification Regarding the detailed standard, please contact info@shjnj.com 3. Package 1 kg/bag; 5 kgs/bag; It can also be packed according to the requirements 4. Product source Produced by fermentation in China 5. Document support SMF and DMF are available 6. Supply Annual capacity: 5 MT; Stable supply for more than 10 years If you need, Please contact us:info@shjnj.com |